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Use Control-F or the Search function on your computer with your terminal SNP, Cluster Number or Project Member Number to find any remarks pertinent to your data.
Despite the addition of hundreds of markers now available from advanced SNP testing, STR markers 1 through 111 (Table 1) still remain the most useful. Analysis of additional markers remains speculative
Cluster 3000 (PF4135)
Advanced Y testing would refine the SNP stream of these project members.
Cluster 3001
Driscolls under I-A1115 are outliers to other I-PF4135 Driscolls. They show a two-step mutation on Y-GGAAT-1B07 (#92 in Table 1), a slow mutating marker. If 11 was the older value, it lingered long enough for cousin branch I-A13665 to retain it. All other I-PF4135 Driscolls carry the value of 9 on this marker.
Cluster members do not reveal any particular geographic origin pattern. One reports ancestry from Ballymoney, Dunmanway; the other from Glin, Limerick.
Mutations of interest:
Y-GGAAT-1B07(#92, Table 1) = 11. This is a slow-mutating marker. The value is shared with very distant Driscoll branches I-A13665 in clusters 3025 and 3030. All other Driscolls carry the value 9.
FTY157(#387, Table 5) = 7. This value = 9 for all other advance tested I-PF4135 Driscolls (modal).
FTY194(#395, Table 5) = 13. This value = 12 for all other advance tested I-PF4135 Driscolls (modal).
FTY267(#417, Table 5) = 13. This value = 12 for all other advance tested I-PF4135 Driscolls (modal).
DYS514(#430, Table 5) = 15, also showing up in remote cousin Driscoll branch I-A13665 in Cluster 3025; remaining advanced tested Driscolls are 16 (modal) and a few 17.
DYF393u3(#591, Table 7) = 22, also showing up in remote cousin Driscoll branch I-A13665 in Cluster 3025; remaining advanced tested Driscolls are 23 (modal) with one at 24.
FTY1107 (#624, Table 7) = 13, also showing up in remote cousin Driscoll branch I-A13665 in Cluster 3025 and downstream I-A13664 in Cluster 3035; remaining advanced tested Driscolls are 12 (modal).
FTY110 (#628, Table 7) = 14, also showing up in remote cousin Driscoll branch I-A13665 in Cluster 3006 and downstream I-A13664 in Cluster 3035; remaining advanced tested Driscolls are 15 (modal).
Cluster 3025 (A13665/Y31631)
I-A13665/Y31631 is upstream to the I-A14359 Driscolls, where the bulk of I-PF4135 Driscolls lie.
70494771 does not have a Driscoll STR match on 111 markers but is GD=13 to his nearest match.
See also Cluster 3030.
Mutations of interest:
Y-GGAAT-1B07(#92, Table 1) = 11. This is a slow-mutating marker. The value is shared with the distant Driscoll outlier branch I-A11115 in Cluster 3001. All other Driscolls carry the value 9 (modal).
DYS514(#430, Table 5) = 15, also showing up in remote outlier Driscoll branch I-A11115 in Cluster 3001; remaining advanced tested Driscolls are 16 (modal) and a few 17.
DYF393u3(#591, Table 7) = 22, also showing up in remote outlier Driscoll branch I-A11115 in Cluster 3001; remaining advanced tested Driscolls are 23 (modal) with one at 24.
FTY1107 (#624, Table 7) = 13, also showing up downstream in I-A13664 in Cluster 3035 and in remote outlier Driscoll branch I-A11115 in Cluster 3001 and downstream I-A13664 in Cluster 3035; remaining advanced tested Driscolls are 12 (modal).
FTY110 (#628, Table 7) = 14, also showing up downstream I-A13664 in Cluster 3035 and in outlier Driscoll branch I-A13665 in Cluster 3025; remaining advanced tested Driscolls are 15 (modal).
Cluster 3006 (A13665/Y1361)
I-A13665/Y31631 is upstream to the I-A14359 Driscolls. So far, all project testers with this terminal SNP exhibit Y-GGAAT-1B07 (#92, Table 1) = 11 as in the outlier branch in cluster 3001.
Member 43666169 has not confirmed his terminal SNP, but exhibits what could be a correlative 11 on Y-GGAAT-1B07 (#92). He is not a STR match to 70494771 in Cluster 3006 but is an STR match to a man whose surname looks like a corruption of Driscoll and whose terminal SNP is I-A13665.
See also Cluster 3025.
Cluster 3035
This project member has Driscoll matches, though their terminal SNPs are further downstream from I-A13664. We expect this member's terminal SNP to be further refined over time.
Mutations of interest:
FTY129(#298, Table 4) = 9. So far this is unique to this Driscoll at I-A13664 > BY133999. We are waiting to see if this constitutes a correlation between a particular STR value and a specific SNP branch.
FTY1107 (#624, Table 7) = 13, also showing up in parent Driscoll branch I-A13665 in Cluster 3006 and in remote outlier Driscoll branch I-A11115 in Cluster 3001; remaining advanced tested Driscolls are 12 (modal).
FTY110 (#628, Table 7) = 14, also showing up in parent Driscoll branch I-A13665 in Cluster 3006 and in remote outlier Driscoll branch I-A11115 in Cluster 3001; remaining advanced tested Driscolls are 15 (modal).
Cluster 3040 (FT46638)
Resolution of the terminal SNP of this cluster was "stuck" at I-A14359 for a long time, in March 2021 it has been resolved to I-FT46638.
One individual in this cluster is closest to the I-PF4135 Driscoll modal, with GD=3. A match has been found summer 2021, GD = 6.
Mutations shared between the two members of this cluster:
- DYS441(#91, table 1) = 14, whereas the modal = 15. (Notably, the outlier branch in Cluster 3001 is also 14.)
- FTY112(#382, table 4) = 13, whereas the modal = 14. (There are a few others in the dataset with FTY112 = 13, notably those with terminal SNP A19162.)
- DYS612u5(#668, table 8) = 23, whereas the modal is 22.
Cluster 3045
With terminal SNP I-Y37101, the project member in this cluster has plenty of Driscoll matches at 67 markers, though they get branched off by 111 markers. We can probably expect further refinement of the terminal SNP.
There appears to be a mutation DYS510 (#108) = 15, unique among the known I-PF4135 Driscolls in the project.
DYS518u3 (#600, Table #7) = 16 appears to be unique among the I-P37 project Driscolls whose extended markers are analyzable.
Ancestry of this one member is from the Kilmacabea / Ross parish area between Skibbereen and Clonakilty districts.
Cluster 3050 (Y112683)
SNP I-Y112683 so far is showing a good correlation to STR marker DYS390(#2, table 1)=23. On that basis, a number of project members were recategorized in 2020. This is a leap of faith. Interested project members will need to do Big Y to confirm.
Assuming the addition of the non-confirmed members was the right thing to do, this cluster is now the largest subclade cluster under I-A14359.
Although some cluster members show each other as matches, some are cut off from each other's STR match lists. DYS712(#94), a highly volatile marker, is one factor separating these members.
Two members have known ancestry from Caheragh parish. Remarkably their ancestors were practically within shouting distance of each other, but they are not Y111 matches. Another member has ancestry from Skull.
The size of the cluster, plus the Genetic Distances between members, leads the project to believe that the TMRCA for Y112683 could push back a bit, and that this will eventually split into multiple subclades.
80447821 has a mutation DYS607(#31, Table 1) = 14 that is also exhibited by Cluster 3075, a different SNP subclade. For now, his placement is a contest between the value for DYS607 and DYS390. We continue to wait for further terminal SNP refinement of his Big Y results. One reason for the lack of STR matches is the extra copies he shows on multicopy markers DYS459, DYS464, and CDY - adding three to his genetic distance counts. Genetic Distance calculations have been redone to account for this. See Genetic Distance table remarks. Another item in favor of placement in Cluster 3050 is autosomal DNA matching to someone descended from another Driscoll lineage in this cluster - though he autosomally matches other Driscolls too.
Other mutations of interest:
Members exhibit DYS574(#479, Table 6) = 9 or No Call. Remaining Driscolls exhibit 10 (modal) or No Call.
Cluster 3055
This cluster is under BY37208 and seems closely bound to Cluster 3056. These two clusters may undergo future revision.
Member 20872031 is tentatively placed in this cluster until more information is available.
Most members in these clusters have known ancestry from around Bantry, Kilcrohane, Goleen - areas that wrap around southern Cork. Their genetic distances have been sufficiently encouraging to consider them a lineage. These extreme southern clusters are illustrated in the archived diagrams.
DYS520 (#59) = 19 seems indicative of these Driscolls. There may be a STR-SNP correlation.
Mutations on super-volatile marker DYS712 (#94) put a little extra distance between 20872031 and other members of these clusters.
Cluster 3065 (BY90072)
I-A19162 is developing two and possibly three subclades.
Two testers are known distant cousins from Skeaf, Kilmoloda. Project member 10499705 represents that lineage.
The other project member is still actively researching their Cork ancestry.
The two project members shown here share the following mutations:
- DYS607 (#31, Table 1) = 14, which is not common among our known I-PPF4135 Driscolls.
- Volatile DYS576 (#32, Table 1) = 17 uniformly in this cluster, though not entirely unique among the I-PF4135 Driscolls.
- DYS444(#57, Table 1) = 13, which seems unique to I-PF4135 Driscolls in the project.
Cluster 3060 (A19162)
Project members falling in this cluster have documented ancestry from Ashtabula, Ohio, which in turn is believed to have come from the parish of Skull in West Cork.
Another project member has ancestry from Ardagh, Tullagh parish, that ended up in Grass Valley, Australia.
The Australia member has a mutation DYS712(#94) = 26. The Skull members are DYS712 = 22. The modal = 23. So the value on this marker for the Australia branch seems to have "exploded" away from other Driscolls. DYS712 is a highly volatile marker. Though we like to think of mutations as occurring as no more than one step at a time when one occurs, it is entirely possible they could take more than one step in a generation.
Their shared mutation of DYS452 (#87, Table 1) = 33 is ALMOST unique to this cluster. The modal = 32.
Cluster 3070 (BY42560)
This project member has a Driscoll match who has not performed Big Y.
His ancestry is thought to be from the parish of Ardfield, within the Clonakilty district.
Compared to Cluster 3075, he is at least GD=15 on the STR markers.
The common relationship under I-BY42560 is puzzling. There are some mutations on volatile markers that separate him from Cluster 3075 which would account for some of the Genetic Distance. But there are also a number of separating mutations on more slowly mutating markers.
We may eventually see either an older date for BY42560, or a reclassification of this or Cluster 3018 under another terminal SNP.
Cluster 3075 (BY54260)
The project members in this cluster constitute a PEDIGREE. The two project members are patriline 2C cousins (different great-grandmothers.) Ancestry is from the southwest area of Caheragh parish, close to the boundaries of Skull and Aghadown parishes. Members know who their great-grandfather was (b.c. 1842). Of the known brothers to this ancestor, it is believed their sons all died childless; thus there are no surviving paternal line descendants from the brothers.
Shared mutations:
- DYS607(#31, Table 1) = 14, almost unique to this cluster.
- DYS710(#68, Table 1) = 34; this is a more volatile marker, and could be a recent mutation.
Cluster 3080 (BY86789)
So far, I-BY86789 has not yet been pinpointed in Ireland, nor have project members genealogically traced their ancestry back to a specific Ireland location.
These members share a mutation DYS522(#80, Table 1) = 10. The modal = 11.
Also unique or nearly unique to this cluster is DYS389II (#13, Table 1) = 29. The modal = 30. DYS510 (#108, Table 1) = 18. The modal = 17.
Members also show the following mutations on advanced STR markers:
DYS581(#180, Table 2) = 9; modal = 8.
Cluster 3085 (BY176167)
Some members have known ancestry from Skull and Skibbereen, particularly around Castlehaven. One member may have ancestry from Cork City. The other has a known name change from Driscoll enroute to or upon settling in Australia and has not traced ancestry back to a specific Ireland location. Member 59530551 has known ancestry from Virginia, USA.
DYS385 (#5-6) = 12-17 is carried by this cluster and subclade FT3387 (cluster 3095). The other BY176167 grouping (cluster 3090) does not carry 12-17, so a split might have occurred here.
Those in this cluster carry conflicting values for DYS441(#91, Table 1): 15 or 16. Cluster 3090(BY176167) shows DYS441 = 16. Cluster 3095 (FT3387), which is a subclade, carries DYS441 = 15. When compared to other Driscolls, 16 might be the "newer" mutation.
Cluster 3090 (BY176167)
Almost all members under I-BY176167 have not yet conclusively identified their geographic origins in Ireland. Non expert level testers in this cluster have not done Big Y so their placement internally in the project is inconclusive.
DYS385 (#5-6) = 12-17 is carried by cluster 3085 and subclade FT3387 (cluster 3095), but not this cluster. If this is significant, we might expect to see this cluster resolve to a terminal SNP separate from FT3387.
Cluster 3095 (FT3387)
This lineage is under I-BY176167 > FT3387.
Known ancestry for members of this cluster is from Castlehaven.
As in cluster 3085 (BY176167), DYS385ab (#5-6, Table #1) = 12-17. The project modal is 12-16.
The placing of 91566431 is a tossup between this cluster and 3085.
Mutations of interest:
- Though mutation DYS456(#30, Table #1) = 16 is not entirely unique to this cluster, it is uniformly across it. The modal = 17.
- FTY648(#653, Table #7) = 9. This value is shared by one member in I-BY176167 Cluster 3085. For all remaining known I-PF4135 Driscolls having tested out Big Y, this value = 8.
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